Position title: Graduate Student
B.S. Biomedical Engineering, Boston University
Chemically defined culture environments to deconstruct extracellular matrix influences on stem cell fate and tissue morphogenesis.
M.R. Zanotelli, H. Ardalani, J. Zhang, Z. Hou, E.H. Nguyen, S. Swanson, B.K. Nguyen, J. Bolin, A.W. Xie, L. Bischel, R. Stewart, A. Elwell, D.J. Beebe, J.A. Thomson, M.P. Schwartz, and W.L. Murphy (2016) Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels. Acta Biomaterialia, In Press.
S.K. Schmitt, D.J. Trebatoski, J.D. Krutty, A.W. Xie, B. Rollins, W.L. Murphy, and P. Gopalan (2016) Peptide conjugation to a polymer coating via native chemical ligation of azlactones for cell culture. Biomacromolecules 17, 1040-1047.
S.K. Schmitt, A.W. Xie, R.M. Ghassemi, D.J. Trebatoski, W.L. Murphy, and P. Gopalan (2015) Polyethylene glycol coatings on plastic substrates for chemically defined stem cell culture. Adv Healthc Mater 4, 1555-1564.
A.W. Xie*, A.S. Khalil*, and W.L. Murphy (2013) Context clues: The importance of stem cell-material interactions. ACS Chem Biol 9, 45-56. *Equal contribution
C. Williams, A.W. Xie, S. Emani, M. Yamato, T. Okano, S.M. Emani, and J.Y. Wong (2012) A comparison of human smooth muscle and mesenchymal stem cells as potential cell sources for tissue engineered vascular patches. Tissue Eng Part A 18, 986-998.
C. Williams, A.W. Xie, M. Yamato, T. Okano, and J.Y. Wong (2011) Stacking of aligned cell sheets for layer-by-layer control of complex tissue structure. Biomaterials 32, 5625-5632.
Awards & Honors:
2016 Vilas Research Travel Award
NSF Graduate Research Fellowship
NIH Biotechnology Training Program Predoctoral Fellowship
A.W. Xie, W.L. Murphy. Substrates for generation of controlled human pluripotent stem cell colony size and shape. U.S. Patent Application, Continuation in part, Filed 2014.