Dr. Cheryl Soref

Department Affiliation:

Orthopedics and Rehabilitation

Education Background:

Ph.D. Neurobiology, Cell and Molecular Biology, Duke University
B.S. Genetics, University of Wisconsin-Madison

Research Description:

Using undifferentiated stem cells to derive a variety of cell types for 2D and 3D tissue modeling

Publications:

1. Soref, C. M. and W. E. Fahl.  2014.  Optimum Topical Delivery of Adrenergic Agonists to Oral Mucosa Vasculature. Pharmaceutical Research. [Epub ahead of print]
2. Soref, C. M. and W. E. Fahl.  2014. A new strategy to prevent chemotherapy and radiotherapy-induced alopecia using topically applied vasoconstrictor.  Int J Cancer. [Epub ahead of print]
3. Soref, C. M. and W. E. Fahl.  2014.  A New Topical Vasoconstrictor-Based Strategy for Prevention of Oral Mucositis. Oral Surg Oral Med Oral Pathol Oral Radiol. 117(4):  454-61.
4. Burke, J. M., and C. Soref.  1988.  Topographical Variation in Growth in Cultured Bovine Retinal Pigment Epithelium.  Investigative Ophthalmology and Visual Science 29(12):  1784-1788.
5. Winey, M., L. Mathison, C. M. Soref, and M. R. Culbertson.  1989.  Distribution of introns in frameshift-suppressor proline-tRNA genes of Saccharomyces cerevisiae.  Gene 76:  89-97.
6. Mathison, L., M. Winey, C. Soref, M. R. Culbertson, and G. Knapp.  1989. Mutations in the Anticodon Stem Affect Removal of Introns from Pre-tRNA in Saccharomyces cerevisiae.  Molecular and Cellular Biology 9(10):  4220-4228.
7. Hao, Y., C. M. Soref, C. G. Gerke, and F. Wong.  1992a.  The Visual Pigment Gene Family and Distribution of Photoreceptors in the Pig Retina.  Investigative Ophthalmology and Visual Science 33(4):  1004.
8. Soref, C. M., and F. Wong.  1994a.  Characterization of an Opsin Promoter Element:  Ret 1.  Investigative Ophthalmology and Visual Science 35(4):  1703.
9. Di, Y.-P., C. M. Soref, Y. H. Zhao, and R. Wu.  1999a.  Characterization and regulation of an airway epithelial cell-specific novel gene which belongs to the short-chain alcohol dehydrogenase/reductase (SDR) gene family.  Am. J. of Respir. and Crit. Care Med. 159(3):  A37.
10. Soref, C. M., Y.-P. Di, Y. H. Zhao, and R. Wu.  2000a.  Characterization of the expression of a novel airway epithelial cell-specific gene with a putative retinol dehydrogenase activity.  Am. J. of Respir. and Crit. Care Med. 161(3):  A259.
11. Soref CM, Di YP, Hayden L, Zhao YH, Satre MA, Wu R. 2001.  Characterization of a novel airway epithelial cell-specific short chain alcohol dehydrogenase/reductase gene whose expression is up-regulated by retinoids and is involved in the metabolism of retinol.  J Biol Chem. 276(26):  24194-202.
12. Soref, C. M. and R. Wu.  2002a.  Identification of an hRDH-TBE Ortholog in the mouse genome.  Am. J. of Respir. and Crit. Care Med. 165(8):  A70.
13. Peebles, D. D., C. M. Soref, R. R. Copp, A. L. Thunberg, and W. E. Fahl.  2012. ROS-Scavenger and Radioprotective Efficacy of the New PrC-210 Aminothiol. Radiat Res. Jul;178(1):  57-68.
14. Soref, C. M., T. A. Hacker, and W. E. Fahl.  2012.  A New Orally Active, Aminothiol Radioprotector-free of Nausea and Hypotension Side Effects at its Highest Radioprotective Doses.  Journal of Radiation Oncology, Biology & Physics 82 (5):  e701-707.
15. Copp, R. R., D. D. Peebles, C. M. Soref, and W. E. Fahl.  2013.  Radioprotection and Toxicity of a New Family of Aminothiol Analogs. Int. J. Radiation Biol. 89 (7):  485-492.

Awards & Honors:

Grants and Fellowships

• Individual National Research Service Award, NIH (2000-2002).
• American Lung Association Research Training Fellowship (1999-2000)
• Postdoctoral Training Grant in Cardiovascular and Neurophysiology (1997-1998)
• NIH Predoctoral Training Grant, Duke University Program in Cell and Molecular Biology (1989-1992)

Honors

• 1994    Member of Sigma Xi
• 1986    Gamma Delta Sigma
• 1985    Golden Key National Honor Society
• 1982    Sigma Epsilon Sigma
• 1982    Phi Eta Sigma